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‘Sticky balls’ may stop cancer spreading

first_imgHealthLifestyle ‘Sticky balls’ may stop cancer spreading by: – January 7, 2014 Share Sharing is caring! Breast cancers can spread to other tissues in the bodyCancer-killing “sticky balls” can destroy tumour cells in the blood and may prevent cancers spreading, early research suggests.The most dangerous and deadly stage of a tumour is when it spreads around the body.Scientists at Cornell University, in the US, have designed nanoparticles that stay in the bloodstream and kill migrating cancer cells on contact.They said the impact was “dramatic” but there was “a lot more work to be done”.One of the biggest factors in life expectancy after being diagnosed with cancer is whether the tumour has spread to become a metastatic cancer.“About 90% of cancer deaths are related to metastases,” said lead researcher Prof Michael King.On the trailThe team at Cornell devised a new way of tackling the problem.They attached a cancer-killing protein called Trail, which has already been used in cancer trials, and other sticky proteins to tiny spheres or nanoparticles.When these sticky spheres were injected into the blood, they latched on to white blood cells.Tests showed that in the rough and tumble of the bloodstream, the white blood cells would bump into any tumour cells which had broken off the main tumour and were trying to spread.The report in Proceedings of the National Academy of Sciences showed the resulting contact with the Trail protein then triggered the death of the tumour cells.Prof King told the BBC: “The data shows a dramatic effect: it’s not a slight change in the number of cancer cells.“The results are quite remarkable actually, in human blood and in mice. After two hours of blood flow, they [the tumour cells] have literally disintegrated.”He believes the nanoparticles could be used used before surgery or radiotherapy, which can result in tumour cells being shed from the main tumour.It could also be used in patients with very aggressive tumours to prevent them spreading.However, much more safety testing in mice and larger animals will be needed before any attempt at a human trial is made.So far the evidence suggests the system has no knock-on effect for the immune system and does not damage other blood cells or the lining of blood vessels.But Prof King cautioned: “There’s a lot of work to be done. Various breakthroughs are needed before this could be a benefit to patients.”By James GallagherBBC News Sharecenter_img Tweet 21 Views   no discussions Sharelast_img read more

Travel Industry Exhibition set to take off with industry supporter ATA

first_imgATAS will provide content for the seminar program, which will give accreditation to the educational component of the show.Event director, Pascal Ibrahim commented, “The exhibition is an important contributor to the professional development of the industry and the partnership with ATAS ensures we provide sessions that will really benefit visitors and exhibitors.We are passionate about helping our travel clients expand into new markets, explore new sales channels and win new customers.”Australian Federation of Travel Agents chief executive Jayson Westbury said:“ATAS is all about elevating industry standards. We have already seen over 2,500 agency locations across Australia become ATAS – travel accredited and improve their business procedures and practices in the process.Visitors experience the latest innovations in destinations, hotels, air products, cruises, tours, packages, travel technology, travel agency groups, travel recruiters, industry organisations and more.The 2015 exhibition will take place 16- 17 July 2015 at the Sydney Exhibition Centre at Glebe Island. Source = ETB News: Megan Tranlast_img read more